PT-141 (Bremelanotide) 10 mg – Research-Grade Peptide
Product Summary:
Content: 10 mg lyophilized PT-141 (Bremelanotide) peptide
Purity: ≥ 99%
Formula: C₅₀H₆₈N₁₄O₁₀
Molecular Weight: 1025.18 g/mol
Intended Use: For laboratory and research use only
Amino Acid Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Origin: A synthetic melanocortin receptor agonist derived from α-MSH (alpha-melanocyte-stimulating hormone)
What is PT-141?
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide developed from melanocortin analogs. Unlike PDE5 inhibitors, it acts primarily on the central nervous system by stimulating melanocortin receptors, particularly MC3R and MC4R, which are involved in sexual behavior and arousal pathways.
Originally investigated for pigmentation research, PT-141 was later found to influence sexual arousal pathways independently of vascular mechanisms.
Potential Benefits in Research
Central Nervous System Activation:
PT-141 acts on melanocortin receptors in the hypothalamus, influencing sexual motivation and behavioral arousal pathways.
Sexual Function Research:
Studied for its role in both male and female sexual response independent of nitric oxide pathways, making it mechanistically distinct from PDE5 inhibitors.
Neuromodulation:
Research suggests potential effects on dopamine-related reward and motivation circuits.
Vascular Independence:
Unlike traditional erectile function agents, PT-141 does not primarily act via vasodilation, but via central neurochemical pathways.
Legal Notice and Usage Disclaimer
For Research Use Only: PT-141 is intended strictly for laboratory research and scientific investigation. It is not approved for human consumption.
FDA Status: Bremelanotide is FDA-approved only in specific pharmaceutical formulations for prescription use under strict medical supervision; this research form is not approved.
WADA Classification: May be prohibited in competitive sports under anti-doping regulations.
Product Details
Packaging: 10 mg of lyophilized powder in a sterile glass vial
Storage: Store at 2–8°C (refrigerated). Protect from light and moisture.
Solubility: Soluble in bacteriostatic water or appropriate sterile solvents
Stability: Best used shortly after reconstitution under laboratory conditions
Scientific References
Intranasal and central melanocortin receptor modulation in sexual function research
Journal of Sexual Medicine (clinical review literature)
Bremelanotide (PT-141) pharmacology and melanocortin receptor activity
Nature Reviews Drug Discovery
Melanocortin pathways in sexual arousal and behavior regulation
Endocrine Reviews
Clinical development of PT-141 for hypoactive sexual desire disorder
FDA clinical trial documentation summaries
Contact & Orders
At TFLL Pharma, we are committed to providing high-purity, research-grade peptides to support advanced scientific and pharmacological research. For further information or to place an order for PT-141 10 mg, please contact our team.
Note: This product is strictly intended for laboratory and research use only. It is not suitable for human consumption. All use must comply with applicable local regulations and ethical research standards.
